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Last updated: 2016/11/27
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BIRC3 polyclonal antibody

  • Catalog # : PAB18987
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of BIRC3.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human BIRC3.
  • Sequence:
  • C-SQPTFPSSVT
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 70
  • Reactivity:
  • Human
  • Specificity:
  • Reported variants represent identical protein: NP_892007.1, NP_001156.1
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL in Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • BIRC3 polyclonal antibody (Cat # PAB18987, 0.1 ug/mL) staining of HeLa lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 330
  • Gene Name:
  • BIRC3
  • Gene Alias:
  • AIP1,API2,CIAP2,HAIP1,HIAP1,MALT2,MIHC,RNF49
  • Gene Description:
  • baculoviral IAP repeat-containing 3
  • Gene Summary:
  • The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq
  • Other Designations:
  • TNFR2-TRAF signaling complex protein,apoptosis inhibitor 2,baculoviral IAP repeat-containing protein 3,inhibitor of apoptosis protein 1,mammalian IAP homolog C
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