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Last updated: 2017/3/26
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SNAP23 polyclonal antibody

  • Catalog # : PAB18976
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of SNAP23.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at C-terminus of human SNAP23.
  • Sequence:
  • C-TDKADTNRDR
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 20-26
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both isoforms (NP_003816.2; NP_570710.1). Amino acid numbering in name refers to NP_003816.2 sequence.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:2000)
    Western Blot (0.2-0.6 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL in Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • SNAP23 polyclonal antibody (Cat # PAB18976, 0.2 ug/mL) staining of PBMCs lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8773
  • Protein Accession#:
  • NP_003816.2;NP_570710.1
  • Gene Name:
  • SNAP23
  • Gene Alias:
  • HsT17016,SNAP23A,SNAP23B
  • Gene Description:
  • synaptosomal-associated protein, 23kDa
  • Gene Summary:
  • Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000161263,synaptosomal-associated protein 23
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