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Last updated: 2017/7/23
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CYP24A1 polyclonal antibody

  • Catalog # : PAB18975
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CYP24A1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human CYP24A1.
  • Sequence:
  • C-RKYDIQATDN
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 50
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_000773.2; NP_001122387.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL in Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CYP24A1 polyclonal antibody (Cat # PAB18975, 0.1 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1591
  • Protein Accession#:
  • NP_000773.2;NP_001122387.1
  • Gene Name:
  • CYP24A1
  • Gene Alias:
  • CP24,CYP24,MGC126273,MGC126274,P450-CC24
  • Gene Description:
  • cytochrome P450, family 24, subfamily A, polypeptide 1
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • 1,25-@dihydroxyvitamin D3 24-hydroxylase,24-OHase,OTTHUMP00000031314,cytochrome P450 family 24 subfamily A polypeptide 1,cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase),exo-mitochondrial protein,vitamin D 24-hydroxylase
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