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Last updated: 2016/10/23
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CSF1R polyclonal antibody

  • Catalog # : PAB18945
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CSF1R.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human CSF1R.
  • Sequence:
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 200
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (0.2-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL in Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • HEK293 lysate (10ug protein in RIPA buffer) overexpressing human CSF1R with C-terminal MYC tag probed with CSF1R polyclonal antibody (Cat # PAB18945, 1 ug/mL) in Lane A and probed with anti-MYC Tag (1/1000) in lane C.
    Mock-transfected HEK293 probed with CSF1R polyclonal antibody (Cat # PAB18945) (1 mg/mL) in Lane B.
    Primary incubations were for 1 hour. Detected by chemiluminescence.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1436
  • Gene Name:
  • CSF1R
  • Gene Alias:
  • Gene Description:
  • colony stimulating factor 1 receptor
  • Gene Summary:
  • The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq
  • Other Designations:
  • CD115 antigen,FMS proto-oncogene,McDonough feline sarcoma viral (v-fms) oncogene homolog,macrophage colony stimulating factor I receptor,soluble CSF1R variant 1
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