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KREMEN1 polyclonal antibody

  • Catalog # : PAB1891
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of KREMEN1.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human KREMEN1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of KREMEN1 (arrow) using KREMEN1 polyclonal antibody (Cat # PAB1891). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the KREMEN1 gene (Lane 2) (Origene Technologies).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with KREMEN1 polyclonal antibody (Cat # PAB1891), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • KREMEN1
  • Gene Alias:
  • FLJ31863,KREMEM1,KREMEN,KRM1
  • Gene Description:
  • kringle containing transmembrane protein 1
  • Gene Summary:
  • This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028977,kringle-coding gene marking the eye and the nose,kringle-containing transmembrane protein 1
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