CASP4 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with CASP4 polyclonal antibody (Cat # PAB18847) at 1 : 250 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded human tonsil tissue showing cytoplasmic staining with CASP4 polyclonal antibody (Cat # PAB18847) at 1 : 100 dilution.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CASP4.
Immunogen
A synthetic peptide corresponding to 14 amino acids of human CASP4.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
ELISA (1:20000-1:80000)
Western Blot (1:200-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with CASP4 polyclonal antibody (Cat # PAB18847) at 1 : 250 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded human tonsil tissue showing cytoplasmic staining with CASP4 polyclonal antibody (Cat # PAB18847) at 1 : 100 dilution.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — CASP4
Entrez GeneID
837Protein Accession#
NM_001225Gene Name
CASP4
Gene Alias
ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX
Gene Description
caspase 4, apoptosis-related cysteine peptidase
Omim ID
602664Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
apoptotic cysteine protease Mih1/TX|caspase 4|caspase 4, apoptosis-related cysteine protease
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com