ABCE1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ABCE1.
Immunogen
A synthetic peptide corresponding to amino acids at C-terminus of human ABCE1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
ELISA (1:160000)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with ABCE1 polyclonal antibody (Cat # PAB18823) at 1 : 1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ABCE1
Entrez GeneID
6059Protein Accession#
P61221Gene Name
ABCE1
Gene Alias
ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I
Gene Description
ATP-binding cassette, sub-family E (OABP), member 1
Omim ID
601213Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family E, member 1|RNase L inhibitor|ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor
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Interactome
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Disease
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