ADAMTS5 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ADAMTS5.
Immunogen
A synthetic peptide corresponding to 15 amino acids at C-terminus of human ADAMTS5.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
ELISA (1:160000)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of human fetal brain lysate with ADAMTS5 polyclonal antibody (Cat # PAB18813) at 1 : 500 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ADAMTS5
Entrez GeneID
11096Gene Name
ADAMTS5
Gene Alias
ADAMTS11, ADMP-2, FLJ36738
Gene Description
ADAM metallopeptidase with thrombospondin type 1 motif, 5
Omim ID
605007Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage. [provided by RefSeq
Other Designations
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)|aggrecanase-2
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Interactome
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Disease
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