HEK293 overexpressing human BICC1 with N-terminal FLAG, probed with rabbit anti-BCC1 in Western Blot after IP using either BICC1 polyclonal antibody (Cat # PAB18761) or anti-FLAG antibody in the presence or absence of SDS. Lane 1: native, PAB18761. Lane 2: native, anti-Flag. Lane 3: SDS, PAB18761. Lane 4: SDS, anti-Flag.
This gene encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product. [provided by RefSeq