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Last updated: 2016/12/4
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PYGM polyclonal antibody

  • Catalog # : PAB1876
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PYGM.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PYGM.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:10-50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of PYGM (arrow) using PYGM polyclonal antibody (Cat # PAB1876). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PYGM gene (Lane 2) (Origene Technologies).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with PYGM polyclonal antibody (Cat # PAB1876) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5837
  • Protein Accession#:
  • NP_005600;P11217
  • Gene Name:
  • PYGM
  • Gene Alias:
  • -
  • Gene Description:
  • phosphorylase, glycogen, muscle
  • Gene Summary:
  • This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants
  • Other Designations:
  • McArdle syndrome,glycogen phosphorylase,glycogen storage disease type V,myophosphorylase,phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V)
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