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Last updated: 2016/12/4
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MSLN polyclonal antibody

  • Catalog # : PAB18754
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of MSLN.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human MSLN.
  • Sequence:
  • CPSGKKAREIDES
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 70
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoform 1 and 2 (NP_005814.2; NP_037536.2).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (0.3-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • MSLN polyclonal antibody (Cat # PAB18754) (0.3 ug/mL) staining of human placenta lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_005814.2;NP_037536.2
  • Gene Name:
  • MSLN
  • Gene Alias:
  • CAK1,MPF,SMR
  • Gene Description:
  • mesothelin
  • Gene Summary:
  • An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • megakaryocyte potentiating factor
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