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Last updated: 2016/12/4
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HMGA2 polyclonal antibody

  • Catalog # : PAB18729
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of HMGA2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human HMGA2.
  • Sequence:
  • C-KAAQKKAEATGEK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 18
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_003474.1; NP_003475.1) and is not expected to cross-react with HMGA1.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • HMGA2 polyclonal antibody (Cat # PAB18729) (1 ug/mL) staining of human heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8091
  • Protein Accession#:
  • NP_003474.1;NP_003475.1
  • Gene Name:
  • HMGA2
  • Gene Alias:
  • BABL,HMGI-C,HMGIC,LIPO,STQTL9
  • Gene Description:
  • high mobility group AT-hook 2
  • Gene Summary:
  • This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • High-mobility group protein HMGI-C,high-mobility group (nonhistone chromosomal) protein isoform I-C
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