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Last updated: 2016/12/11
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TPP1 polyclonal antibody

  • Catalog # : PAB18724
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TPP1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human TPP1.
  • Sequence:
  • C-TPSVIRKRYNLTSQD
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 65
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:4000)
    Western Blot (0.3-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • TPP1 polyclonal antibody (Cat # PAB18724) (0.3 ug/mL) staining of human placenta lysate (35 ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1200
  • Gene Name:
  • TPP1
  • Gene Alias:
  • CLN2,GIG1,LPIC,MGC21297
  • Gene Description:
  • tripeptidyl peptidase I
  • Gene Summary:
  • This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq
  • Other Designations:
  • ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease),growth-inhibiting protein 1,lysosomal pepstatin insensitive protease,tripeptidyl aminopeptidase,tripeptidyl-peptidase I
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