ADCYAP1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ADCYAP1.
Immunogen
A synthetic peptide corresponding to amino acids at C-terminus of human ADCYAP1.
Sequence
C-GKRYKQRVKNKGRR
Host
Goat
Theoretical MW (kDa)
25
Reactivity
Human
Specificity
Reported variants represent identical protein: NP_001093203.1, NP_001108.2.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:2000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ADCYAP1 polyclonal antibody (Cat # PAB18702) (1 ug/mL) staining of human hippocampus lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ADCYAP1
Entrez GeneID
116Protein Accession#
NP_001108.2Gene Name
ADCYAP1
Gene Alias
MGC126852, PACAP
Gene Description
adenylate cyclase activating polypeptide 1 (pituitary)
Omim ID
102980Gene Ontology
HyperlinkGene Summary
This gene encodes adenylate cyclase activating polypeptide 1. Mediated by adenylate cyclase activating polypeptide 1 receptors, this polypeptide stimulates adenylate cyclase and subsequently increases the cAMP level in target cells. Adenylate cyclase activating polypeptide 1 is not only a hypophysiotropic hormone, but also functions as a neurotransmitter and neuromodulator. In addition, it plays a role in paracrine and autocrine regulation of certain types of cells. This gene encodes three different mature peptides, including two isotypes, a shorter form and a longer form. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000162201|adenylate cyclase activating polypeptide
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Interactome
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Pathway
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Disease
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