ANKK1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ANKK1.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human ANKK1.
Sequence
C-SRQADPNLHEAEGKT
Host
Goat
Theoretical MW (kDa)
85
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:128000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ANKK1 polyclonal antibody (Cat # PAB18698) (0.1 ug/mL) staining of human substantia nigra lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ANKK1
Entrez GeneID
255239Protein Accession#
NP_848605.1Gene Name
ANKK1
Gene Alias
PKK2
Gene Description
ankyrin repeat and kinase domain containing 1
Omim ID
608774Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq
Other Designations
X-kinase|protein kinase PKK2
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Interactome
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Disease
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