PTPRN polyclonal antibody
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More Files
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Western Blot (Cell lysate)
PTPRN polyclonal antibody (Cat # PAB18679) (0.5 ug/mL) staining of NIH/3T3 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PTPRN.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human PTPRN.
Sequence
C-QGEGNIKKNRHPD
Host
Goat
Reactivity
Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
PTPRN polyclonal antibody (Cat # PAB18679) (0.5 ug/mL) staining of NIH/3T3 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PTPRN
Entrez GeneID
5798Protein Accession#
NP_002837.1Gene Name
PTPRN
Gene Alias
FLJ16131, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Gene Description
protein tyrosine phosphatase, receptor type, N
Omim ID
601773Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq
Other Designations
islet cell antigen 2|islet cell antigen 512|islet cell autoantigen 3|protein tyrosine phosphatase-like N
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Interactome
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Pathway
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Disease
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