TTC8 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TTC8.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human TTC8.
Sequence
C-KEVLKQDNTHVE
Host
Goat
Theoretical MW (kDa)
60
Reactivity
Human
Specificity
This antibody is expected to recognize all reported isoforms (NP_653197.2; NP_938051.1; NP_938052.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:8000)
Western Blot (0.2-0.6 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
TTC8 polyclonal antibody (Cat # PAB18637) (0.2 ug/mL) staining of human testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TTC8
Entrez GeneID
123016Protein Accession#
NP_653197.2;NP_938051.1;NP_938052.1Gene Name
TTC8
Gene Alias
BBS8
Gene Description
tetratricopeptide repeat domain 8
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized. [provided by RefSeq
Other Designations
Bardet-Biedl syndrome type 8
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Interactome
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Disease
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