PEX26 polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of PEX26.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human PEX26.
Sequence
C-QKPNLEGSVSHK
Host
Goat
Theoretical MW (kDa)
33
Reactivity
Human
Specificity
Reported variants represent identical protein: NP_060399.1, NP_001121121.1.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:64000)
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
PEX26 polyclonal antibody (Cat # PAB18622) (0.5 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PEX26
Entrez GeneID
55670Protein Accession#
NP_060399.1Gene Name
PEX26
Gene Alias
FLJ20695, PEX26M1T, Pex26pM1T
Gene Description
peroxisomal biogenesis factor 26
Gene Ontology
HyperlinkGene Summary
This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000195598|peroxin-26|peroxisome assembly protein 26|peroxisome biogenesis disorder, complementation group 8|peroxisome biogenesis disorder, complementation group A|peroxisome biogenesis factor 26
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