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Last updated: 2017/8/13
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PON2 polyclonal antibody

  • Catalog # : PAB18578
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of PON2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human PON2.
  • Sequence:
  • C-EKPRARELRIS
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 40
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.2-0.6 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • PON2 polyclonal antibody (Cat # PAB18578) (0.2 ug/mL) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5445
  • Protein Accession#:
  • NP_000296.2;NP_001018171.1
  • Gene Name:
  • PON2
  • Gene Alias:
  • -
  • Gene Description:
  • paraoxonase 2
  • Gene Summary:
  • This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • A-esterase 2,aromatic esterase 2,paraoxonase nirs,serum aryldialkylphosphatase 2,serum paraoxonase/arylesterase 2
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