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Last updated: 2016/12/4
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IL12RB1 polyclonal antibody

  • Catalog # : PAB18563
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of IL12RB1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human IL12RB1.
  • Sequence:
  • C-HVSVKNHSLDSVS
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 100
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoform 1 (NP_005526.1) only.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (0.3-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • IL12RB1 polyclonal antibody (Cat # PAB18563) (0.3 ug/mL) staining of human peripheral blood lymphocytes lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3594
  • Gene Name:
  • IL12RB1
  • Gene Alias:
  • CD212,IL-12R-BETA1,IL12RB,MGC34454
  • Gene Description:
  • interleukin 12 receptor, beta 1
  • Gene Summary:
  • The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • IL-12 receptor beta component,interleukin-12 receptor beta-1 chain
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