Product Browser

Last updated: 2017/5/21
  • Related Product Showcase

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

DAG1 polyclonal antibody

  • Catalog # : PAB18550
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of DAG1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human DAG1.
  • Sequence:
  • C-HVGKHEYFMHATDK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 100
  • Reactivity:
  • Human
  • Specificity:
  • Reported variants represent identical protein: NP_001159400.1, NP_004384.3.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (0.2-0.6 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • DAG1 polyclonal antibody (Cat # PAB18550) (0.2 ug/mL) staining of human skeletal muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1605
  • Gene Name:
  • DAG1
  • Gene Alias:
  • 156DAG,A3a,AGRNR,DAG
  • Gene Description:
  • dystroglycan 1 (dystrophin-associated glycoprotein 1)
  • Gene Summary:
  • Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants
  • Other Designations:
  • alpha-dystroglycan,beta-dystroglycan,dystroglycan 1,dystrophin-associated glycoprotein-1
  • RSS
  • YouTube
  • Linkedin
  • Facebook