Cttn polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from COS-7 cells, using Cttn polyclonal antibody (Cat # PAB18460).
Peptide "+" means "peptide blocking".
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cacinoma tissue using Cttn polyclonal antibody (Cat # PAB18460).
Peptide "+" means "peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Cttn.
Immunogen
A synthetic peptide corresponding to residues surrounding Y466 of mouse Cttn.
Host
Rabbit
Reactivity
Mouse, Rat
Specificity
This antibody is specific to Cttn.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from COS-7 cells, using Cttn polyclonal antibody (Cat # PAB18460).
Peptide "+" means "peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cacinoma tissue using Cttn polyclonal antibody (Cat # PAB18460).
Peptide "+" means "peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — Cttn
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Publication Reference
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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM.
Hickson I, Zhao Y, Richardson CJ, Green SJ, Martin NM, Orr AI, Reaper PM, Jackson SP, Curtin NJ, Smith GC.
Cancer Research 2004 Dec; 64(24):9152.
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53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.
Mochan TA, Venere M, DiTullio RA Jr, Halazonetis TD.
Cancer Research 2003 Dec; 63(24):8586.
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Contributions of ATM mutations to familial breast and ovarian cancer.
Thorstenson YR, Roxas A, Kroiss R, Jenkins MA, Yu KM, Bachrich T, Muhr D, Wayne TL, Chu G, Davis RW, Wagner TM, Oefner PJ.
Cancer Research 2003 Jun; 63(12):3325.
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Atm deficiency causes an increased frequency of intrachromosomal homologous recombination in mice.
Bishop AJ, Barlow C, Wynshaw-Boris AJ, Schiestl RH.
Cancer Research 2000 Jan; 60(2):395.
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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM.
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