IGF2R polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IGF2R.
Immunogen
A synthetic peptide corresponding to human IGF2R.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody is specific to IGF2R.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using IGF2R polyclonal antibody (Cat # PAB18437).
Peptide "+" means "peptide blocking".Immunofluorescence
Immunofluorescence analysis of HeLa cells, using IGF2R polyclonal antibody (Cat # PAB18437).
Peptide "+" means "peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — IGF2R
Entrez GeneID
3482Protein Accession#
P11717Gene Name
IGF2R
Gene Alias
CD222, CIMPR, M6P-R, MPR1, MPRI
Gene Description
insulin-like growth factor 2 receptor
Omim ID
147280Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for both, insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of IGF2. In mice, the homologous gene is expressed only from the maternal chromosome. [provided by RefSeq
Other Designations
OTTHUMP00000017536|cation-independent mannose-6 phosphate receptor|insulin-like growth factor-2 receptor (mannose-6-phosphate receptor, cation-independent)
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