TGFBR1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TGFBR1.
Immunogen
A synthetic peptide corresponding to residues surrounding S165 of human TGFBR1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody is specific to TGFBR1.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:500-1:1000)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from COLO cells (Lane 1) and HepG2 cells (Lane 2 and 3), using TGFBR1 polyclonal antibody (Cat # PAB18420).
Peptide "+" means "peptide blocking".Immunofluorescence
Immunofluorescence analysis of HeLa cells, using TGFBR1 polyclonal antibody (Cat # PAB18420).
Peptide "+" means "peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — TGFBR1
Entrez GeneID
7046Protein Accession#
P36897Gene Name
TGFBR1
Gene Alias
AAT5, ACVRLK4, ALK-5, ALK5, LDS1A, LDS2A, SKR4, TGFR-1
Gene Description
transforming growth factor, beta receptor 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000021783|activin A receptor type II-like kinase, 53kD|activin A receptor type II-like kinase, 53kDa|activin receptor-like kinase 5|serine/threonine-protein kinase receptor R4|transforming growth factor beta receptor I|transforming growth factor,
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Interactome
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Pathway
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Disease
- Abnormalities
- Adenocarcinoma
- Adenoma
- Aneurysm
- Aortic Aneurysm
- Aortic Rupture
- Asthma
- Atherosclerosis
- Behcet Syndrome
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