RAPGEF1 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using RAPGEF1 polyclonal antibody (Cat # PAB18417).
Peptide "+" means "peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RAPGEF1.
Immunogen
A synthetic peptide corresponding to human RAPGEF1.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is specific to RAPGEF1.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Immunohistochemistry (1:50-1:100)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using RAPGEF1 polyclonal antibody (Cat # PAB18417).
Peptide "+" means "peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — RAPGEF1
Entrez GeneID
2889Protein Accession#
Q13905Gene Name
RAPGEF1
Gene Alias
C3G, DKFZp781P1719, GRF2
Gene Description
Rap guanine nucleotide exchange factor (GEF) 1
Omim ID
600303Gene Ontology
HyperlinkGene Summary
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000064558|guanine nucleotide-releasing factor 2|guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)
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Interactome
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Pathway
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Disease
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