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Last updated: 2016/12/4
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RAPGEF1 polyclonal antibody

  • Catalog # : PAB18417
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of RAPGEF1.
  • Immunogen:
  • A synthetic peptide corresponding to human RAPGEF1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is specific to RAPGEF1.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:100)
    ELISA (1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using RAPGEF1 polyclonal antibody (Cat # PAB18417).
    Peptide "+" means "peptide blocking".
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2889
  • Gene Name:
  • RAPGEF1
  • Gene Alias:
  • C3G,DKFZp781P1719,GRF2
  • Gene Description:
  • Rap guanine nucleotide exchange factor (GEF) 1
  • Gene Summary:
  • This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000064558,guanine nucleotide-releasing factor 2,guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)
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