TGFB1I1 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human heart tissue using TGFB1I1 polyclonal antibody (Cat # PAB18388).
Peptide "+" means "peptide blocking".
Immunofluorescence
Immunofluorescence analysis of HeLa cells, treated with TNF-a (20 nM, 15 mins), using TGFB1I1 polyclonal antibody (Cat # PAB18388).
Peptide "+" means "peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TGFB1I1.
Immunogen
A synthetic peptide corresponding to human TGFB1I1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody is specific to TGFB1I1.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human heart tissue using TGFB1I1 polyclonal antibody (Cat # PAB18388).
Peptide "+" means "peptide blocking".Immunofluorescence
Immunofluorescence analysis of HeLa cells, treated with TNF-a (20 nM, 15 mins), using TGFB1I1 polyclonal antibody (Cat # PAB18388).
Peptide "+" means "peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — TGFB1I1
Entrez GeneID
7041Protein Accession#
O43294Gene Name
TGFB1I1
Gene Alias
ARA55, HIC-5, HIC5, TSC-5
Gene Description
transforming growth factor beta 1 induced transcript 1
Omim ID
602353Gene Ontology
HyperlinkGene Summary
This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
androgen receptor coactivator ARA55
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Interactome
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Publication Reference
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Hic-5 promotes endothelial cell migration to lysophosphatidic acid.
Avraamides C, Bromberg ME, Gaughan JP, Thomas SM, Tsygankov AY, Panetti TS.
American Journal of Physiology. Heart and Circulatory Physiology 2007 Jul; 293(1):H193.
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HIC-5 is a novel repressor of lymphoid enhancer factor/T-cell factor-driven transcription.
Ghogomu SM, van Venrooy S, Ritthaler M, Wedlich D, Gradl D.
The Journal of Biological Chemistry 2006 Jan; 281(3):1755.
Application：IF, Human, HeLa cells.
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Expression of the LIM proteins paxillin and Hic-5 in human tissues.
Yuminamochi T, Yatomi Y, Osada M, Ohmori T, Ishii Y, Nakazawa K, Hosogaya S, Ozaki Y.
The Journal of Histochemistry and Cytochemistry 2003 Apr; 51(4):513.
Application：IHC-P, WB, Human, Brain, Colon, Hearts, Iliopsoas, Mammary gland, Peripheral nerve, Skin, Sweat gland, Uterus.
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Hic-5 promotes endothelial cell migration to lysophosphatidic acid.
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