FAF1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FAF1.
Immunogen
A synthetic peptide corresponding to human FAF1.
Host
Rabbit
Reactivity
Human, Rat
Form
Lyophilized
Purification
Immunoaffinity purification
Concentration
0.5 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis with FAF1 polyclonal antibody (Cat # PAB18292).
1 : Rat testicular tissue lysate. 2 : MM453 whole cell lysate. 3 : MM231 cell lysate. 4 : HeLa whole cell lysate. 5 : SMMC whole cell lysate. 6 : SW 620 cell lysate. -
Gene Info — FAF1
Entrez GeneID
11124Gene Name
FAF1
Gene Alias
CGI-03, FLJ37524, HFAF1s, UBXD12, UBXN3A, hFAF1
Gene Description
Fas (TNFRSF6) associated factor 1
Omim ID
604460Gene Ontology
HyperlinkGene Summary
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq
Other Designations
FAS-associated factor 1|TNFRSF6-associated factor 1|UBX domain protein 3A
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Interactome
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Disease
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Publication Reference
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Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB.
Park MY, Jang HD, Lee SY, Lee KJ, Kim E.
The Journal of Biological Chemistry 2004 Jan; 279(4):2544.
Application:WB-Tr, IP-WB, Human, Mouse, 293, NIH3T3 cells.
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Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB.
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