GRIN1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GRIN1.
Immunogen
A synthetic peptide corresponding to residues surrounding S890 of human GRIN1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody is specific to GRIN1.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from Jurkat cells, using GRIN1 polyclonal antibody (Cat # PAB18250).
Peptide "+" means "peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using GRIN1 polyclonal antibody (Cat # PAB18250).
Peptide "+" means "peptide blocking".Immunofluorescence
Immunofluorescence analysis of NIH/3T3 cells, using GRIN1 polyclonal antibody (Cat # PAB18250).
Peptide "+" means "peptide blocking".Enzyme-linked Immunoabsorbent Assay
-
Gene Info — GRIN1
Entrez GeneID
2902Protein Accession#
Q05586Gene Name
GRIN1
Gene Alias
NMDA1, NMDAR1, NR1
Gene Description
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Omim ID
138249Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
N-methyl-D-aspartate receptor channel, subunit zeta-1|NMDA receptor 1|OTTHUMP00000022678|glutamate [NMDA] receptor subunit zeta 1
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Homocysteine induces the expression of C-reactive protein via NMDAr-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells.
Pang X, Liu J, Zhao J, Mao J, Zhang X, Feng L, Han C, Li M, Wang S, Wu D.
Atherosclerosis 2014 Sep; 236(1):73.
Application:WB-Ti, Human, Aortic artery.
-
Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum.
Dang MT, Yokoi F, Yin HH, Lovinger DM, Wang Y, Li Y.
PNAS 2006 Oct; 103(41):15254.
Application:WB-Ti, Mouse, Mouse brain.
-
Homocysteine induces the expression of C-reactive protein via NMDAr-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com