CDC25C polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CDC25C.
Immunogen
A synthetic peptide corresponding to human CDC25C.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is specific to CDC25C.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CDC25C polyclonal antibody (Cat # PAB18237).
Peptide "+" means "peptide blocking".Immunofluorescence
Immunofluorescence analysis of HepG2 cells, using CDC25C polyclonal antibody (Cat # PAB18237).
Peptide "+" means "peptide blocking".Enzyme-linked Immunoabsorbent Assay
-
Gene Info — CDC25C
Entrez GeneID
995Protein Accession#
P30307Gene Name
CDC25C
Gene Alias
CDC25
Gene Description
cell division cycle 25 homolog C (S. pombe)
Omim ID
157680Gene Ontology
HyperlinkGene Summary
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq
Other Designations
cell division cycle 25C|cell division cycle 25C protein|dual specificity phosphatase CDC25C|m-phase inducer phosphatase 3|mitosis inducer CDC25|phosphotyrosine phosphatase
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
An additional transcript of the cdc25C gene from A431 cells encodes a functional protein.
Bureik M, Rief N, Drescher R, Jungbluth A, Montenarh M, Wagner P.
International Journal of Oncology 2000 Dec; 17(6):1251.
-
Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C.
Wegener S, Hampe W, Herrmann D, Schaller HC.
European Journal of Cell Biology 2000 Nov; 79(11):810.
Application:WB-Ce, Human, HCT-116, HepG2, NT2, Raji, SKNSH, U373MG cells.
-
An additional transcript of the cdc25C gene from A431 cells encodes a functional protein.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com