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Last updated: 2016/10/23
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MED1 polyclonal antibody

  • Catalog # : PAB18212
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MED1.
  • Immunogen:
  • A synthetic peptide corresponding to human MED1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody is specific to MED1.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Immunofluorescence (1:500-1:1000)
    ELISA (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • J Cell Biol. 2001 Aug 20;154(4):799-814.
    Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, Peters JM, Kaya G, Gonzalez FJ, Zakany J, Metzger D, Chambon P, Duboule D, Wahli W.J Cell Biol. 2001 Aug 20;154(4):799-814.
  • Applications
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of HeLa cells, using MED1 polyclonal antibody (Cat # PAB18212).
    Peptide "+" means "peptide blocking".
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 5469
  • Gene Name:
  • MED1
  • Gene Alias:
  • Gene Description:
  • mediator complex subunit 1
  • Gene Summary:
  • The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq
  • Other Designations:
  • PPAR binding protein,PPARG binding protein,thyroid hormone receptor-associated protein complex component TRAP220,thyroid receptor interacting protein 2,vitamin D receptor-interacting protein 230 kD,vitamin D receptor-interacting protein complex component
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