ANXA6 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ANXA6.
Immunogen
A synthetic peptide corresponding to human ANXA6.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is specific to ANXA6.
Form
Liquid
Recommend Usage
Western Blot (1:500~1:1000)
Immunohistochemistry (1:50~1:100)
Immunofluorescence (1:500~1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from 293 cells, using ANXA6 polyclonal antibody (Cat # PAB18085).
Peptide "+" means "with peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ANXA6 polyclonal antibody (Cat # PAB18085).
Peptide "+" means "with peptide blocking".Immunohistochemistry
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
-
Gene Info — ANXA6
Entrez GeneID
309Protein Accession#
P08133Gene Name
ANXA6
Gene Alias
ANX6, CBP68
Gene Description
annexin A6
Omim ID
114070Gene Ontology
HyperlinkGene Summary
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. [provided by RefSeq
Other Designations
annexin VI|annexin VI (p68)|calcium-binding protein p68|calelectrin|calphobindin II
-
Interactome
-
Disease
-
Publication Reference
-
Annexin A6 controls neuronal membrane dynamics throughout chick cranial sensory gangliogenesis.
Shah A, Schiffmacher AT, Taneyhill LA.
Amino Acids 2017 May; 425(1):85.
Application:IHC, WB, Chicken, Chicken embryos.
-
Identification of a novel interaction between the Ca(2+)-binding protein S100A11 and the Ca(2+)- and phospholipid-binding protein annexin A6.
Chang N, Sutherland C, Hesse E, Winkfein R, Wiehler WB, Pho M, Veillette C, Li S, Wilson DP, Kiss E, Walsh MP.
American Journal of Physiology. Cell Physiology 2007 Apr; 292(4):C1417.
Application:IF, Rat, Rat caudal arterial smooth muscle cells.
-
Cholesterol modulates the membrane binding and intracellular distribution of annexin 6.
de Diego I, Schwartz F, Siegfried H, Dauterstedt P, Heeren J, Beisiegel U, Enrich C, Grewal T.
The Journal of Biological Chemistry 2002 Jun; 277(35):32187.
Application:WB-Ce, Mouse, CHO cells.
-
Endocytosis occurs independently of annexin VI in human A431 cells.
Smythe E, Smith PD, Jacob SM, Theobald J, Moss SE.
The Journal of Cell Biology 1994 Feb; 124(3):301.
Application:WB-Tr, Human, A-431 cells.
-
Annexin A6 controls neuronal membrane dynamics throughout chick cranial sensory gangliogenesis.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com