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Last updated: 2016/11/27
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ACTL6A polyclonal antibody

  • Catalog # : PAB18052
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ACTL6A.
  • Immunogen:
  • A synthetic peptide corresponding to human ACTL6A.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody is specific to ACTL6A.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500~1:1000)
    Immunofluorescence (1:500~1:1000)
    ELISA (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from Jurkat cells (Lane 1) and COLO 205 cells (Lane 2 and lane 3), using ACTL6A polyclonal antibody (Cat # PAB18052).
    Peptide "+" means "with peptide blocking".
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of HUVEC cells, using ACTL6A polyclonal antibody (Cat # PAB18052).
    Peptide "+" means "with peptide blocking".
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 86
  • Gene Name:
  • ACTL6A
  • Gene Alias:
  • ACTL6,ARPN-BETA,Arp4,BAF53A,INO80K,MGC5382
  • Gene Description:
  • actin-like 6A
  • Gene Summary:
  • This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq
  • Other Designations:
  • BAF complex 53 kDa subunit,BAF53,BRG1-associated factor,INO80 complex subunit K,actin-related protein 4,hArpN beta
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