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Last updated: 2016/11/27
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RNF7 polyclonal antibody

  • Catalog # : PAB17858
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of RNF7.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human RNF7.
  • Sequence:
  • DACLRCQAENKQE
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 12.7, 9.64
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • RNF7 polyclonal antibody (Cat # PAB17858) (1 ug/mL) staining of human heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9616
  • Gene Name:
  • RNF7
  • Gene Alias:
  • CKBBP1,ROC2,SAG
  • Gene Description:
  • ring finger protein 7
  • Gene Summary:
  • The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000180645,regulator of cullins 2,sensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2,zinc RING finger protein SAG
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