NCR3 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of extracts from A-549 cells, using NCR3 polyclonal antibody (Cat # PAB17794).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NCR3.
Immunogen
A synthetic peptide corresponding to internal of human NCR3.
Host
Rabbit
Reactivity
Human, Rat
Specificity
This antibody detects endogenous levels of total NCR3 protein
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from A-549 cells, using NCR3 polyclonal antibody (Cat # PAB17794).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — NCR3
Entrez GeneID
259197Protein Accession#
O14931Gene Name
NCR3
Gene Alias
1C7, CD337, LY117, MALS, NKp30
Gene Description
natural cytotoxicity triggering receptor 3
Omim ID
611550Gene Ontology
HyperlinkGene Summary
Natural cytotoxicity receptors (NCRs), such as NCR3, are activating natural killer (NK) cell receptors that belong to the immunoglobulin (Ig) superfamily. NCR3 is expressed in all resting and activated NK cells and forms a complex with CD3-zeta (CD3Z, or CD247; MIM 186780) (Sato et al., 2001 [PubMed 11782277]).[supplied by OMIM
Other Designations
OTTHUMP00000029162|OTTHUMP00000038859|OTTHUMP00000038863|lymphocyte antigen 117
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Interactome
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Pathway
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Disease
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Publication Reference
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Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida.
Li SS, Ogbomo H, Mansour MK, Xiang RF, Szabo L, Munro F, Mukherjee P, Mariuzza RA, Amrein M, Vyas JM, Robbins SM, Mody CH.
Nature Communications 2018 Feb; 9:751.
Application：IF, C. neoformans, C. albicans, Human, C. neoformans, C. albicans, YT cells.
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Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida.
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