MYBPC3 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human heart tissue using MYBPC3 polyclonal antibody (Cat # PAB17783).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MYBPC3.
Immunogen
A synthetic peptide corresponding to amino acids 329-378 of human MYBPC3.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total MYBPC3 protein.
Form
Liquid
Recommend Usage
ELISA (1:10000)
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human heart tissue using MYBPC3 polyclonal antibody (Cat # PAB17783).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — MYBPC3
Entrez GeneID
4607Protein Accession#
Q14896Gene Name
MYBPC3
Gene Alias
CMH4, DKFZp779E1762, FHC, MYBP-C
Gene Description
myosin binding protein C, cardiac
Gene Ontology
HyperlinkGene Summary
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq
Other Designations
myosin-binding protein C, cardiac
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Interactome
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Pathway
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Disease
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