Western blot analysis of extracts from LoVo cells (Lane 1 and lane 5), A-549 cells (Lane 2), HUVEC cells (Lane 3) and MCF-7 cells (Lane 4), using HOXB2 polyclonal antibody (Cat # PAB17749). Peptide "+" means "with peptide blocking".
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer. [provided by RefSeq