MARCH5 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MARCH5.
Immunogen
A synthetic peptide corresponding to internal of human MARCH5.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of total MARCH5 protein.
Form
Liquid
Recommend Usage
Immunofluorescence (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Immunofluorescence analysis of A-549 cells, using MARCH5 polyclonal antibody (Cat # PAB17706).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — MARCH5
Entrez GeneID
54708Protein Accession#
Q9NX47Gene Name
MARCH5
Gene Alias
FLJ20445, MARCH-V, MITOL, RNF153
Gene Description
membrane-associated ring finger (C3HC4) 5
Omim ID
610637Gene Ontology
HyperlinkGene Summary
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM
Other Designations
OTTHUMP00000020096|membrane-associated RING-CH protein V|mitochondrial ubiquitin ligase|ring finger protein 153
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