DMGDH polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from HT-29 cells (Lane 1 and lane 3) and A-549 cells (Lane 2), using DMGDH polyclonal antibody (Cat # PAB17693).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DMGDH.
Immunogen
A synthetic peptide corresponding to C-terminus of human DMGDH.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total DMGDH protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HT-29 cells (Lane 1 and lane 3) and A-549 cells (Lane 2), using DMGDH polyclonal antibody (Cat # PAB17693).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — DMGDH
Entrez GeneID
29958Protein Accession#
Q9UI17Gene Name
DMGDH
Gene Alias
DMGDHD, ME2GLYDH
Gene Description
dimethylglycine dehydrogenase
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. [provided by RefSeq
Other Designations
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Pathway
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Disease
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