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Last updated: 2016/12/4
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DMGDH polyclonal antibody

  • Catalog # : PAB17693
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of DMGDH.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human DMGDH.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody detects endogenous levels of total DMGDH protein.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    ELISA (1:20000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from HT-29 cells (Lane 1 and lane 3) and A-549 cells (Lane 2), using DMGDH polyclonal antibody (Cat # PAB17693).
    Peptide "+" means "with peptide blocking".
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • DMGDH
  • Gene Alias:
  • DMGDHD,ME2GLYDH
  • Gene Description:
  • dimethylglycine dehydrogenase
  • Gene Summary:
  • This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. [provided by RefSeq
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