CLN6 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CLN6.
Immunogen
A synthetic peptide corresponding to internal of human CLN6.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total CLN6 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HeLa cells, using CLN6 polyclonal antibody (Cat # PAB17666).
Peptide "+" means "with peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human cervix tissue using CLN6 polyclonal antibody (Cat # PAB17666).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — CLN6
Entrez GeneID
54982Protein Accession#
Q9NWW5Gene Name
CLN6
Gene Alias
FLJ20561, HsT18960, nclf
Gene Description
ceroid-lipofuscinosis, neuronal 6, late infantile, variant
Gene Ontology
HyperlinkGene Summary
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq
Other Designations
CLN6 protein
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Interactomes
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Diseases
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