CEP170 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CEP170.
Immunogen
A synthetic peptide corresponding to internal of human CEP170.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total CEP170 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from Jurkat cells (Lane 1) and HepG2 cells (Lane 2 and lane 3), using CEP170 polyclonal antibody (Cat # PAB17656).
Peptide "+" means "with peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CEP170 polyclonal antibody (Cat # PAB17656).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — CEP170
Entrez GeneID
9859Protein Accession#
Q5SW79Gene Name
CEP170
Gene Alias
FAM68A, KAB, KIAA0470
Gene Description
centrosomal protein 170kDa
Gene Ontology
HyperlinkGene Summary
The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
Other Designations
KARP 1 binding protein|KARP-1-binding protein|XRCC5 binding protein
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Interactome
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Disease
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