PNPLA8 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PNPLA8.
Immunogen
A synthetic peptide corresponding to internal of human PNPLA8.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total PNPLA8 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HeLa cells (Lane 1), A-549 cells (Lane 2) and HUVEC cells (Lane 3 and lane 4), using PNPLA8 polyclonal antibody (Cat # PAB17642).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — PNPLA8
Entrez GeneID
50640Protein Accession#
Q9NP80Gene Name
PNPLA8
Gene Alias
IPLA2(GAMMA), IPLA2-2, IPLA2G
Gene Description
patatin-like phospholipase domain containing 8
Gene Ontology
HyperlinkGene Summary
Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function (Mancuso et al., 2000 [PubMed 10744668]).[supplied by OMIM
Other Designations
iPLA2 gamma|intracellular membrane-associated calcium-independent phospholipase A2 gamma|membrane-associated calcium-independent phospholipase A2 gamma
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Interactome
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Disease
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