Products

Western Blot (Cell lysate)

Western blot analysis of extracts from HepG2 cells (Lane 1), Jurkat cells (Lane 2), COLO cells (Lane 3) and HUVEC cells (Lane 4 and lane 5), using B3GALT1 polyclonal antibody (Cat # PAB17631).
Peptide "+" means "with peptide blocking".

Enzyme-linked Immunoabsorbent Assay

Entrez GeneID

8708

Protein Accession#

Q9Y5Z6

Gene Name

B3GALT1

Gene Alias

MGC126594, beta3Gal-T1

Gene Description

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1

Omim ID

603093

Gene Ontology

Hyperlink

Gene Summary

This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is expressed exclusively in the brain. The encoded protein shows strict donor substrate specificity for UDP-galactose. [provided by RefSeq

Other Designations

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 1|beta-3-galt1