SGCA polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SGCA.
Immunogen
A synthetic peptide corresponding to internal of human SGCA.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total SGCA protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from Jurkat cells (Lane 1), HepG2 cells (Lane 2) and HeLa cells (Lane 3 and lane 4), using SGCA polyclonal antibody (Cat # PAB17604).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — SGCA
Entrez GeneID
6442Protein Accession#
Q16586Gene Name
SGCA
Gene Alias
50-DAG, A2, ADL, DAG2, DMDA2, LGMD2D, SCARMD1, adhalin
Gene Description
sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
Gene Ontology
HyperlinkGene Summary
This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
50kD DAG|sarcoglycan, alpha
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Interactome
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Pathway
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