AASS polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AASS.
Immunogen
A synthetic peptide corresponding to internal of human AASS.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total AASS protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HeLa cells (Lane 1), 293 cells (lane 2 and lane 4) and HUVEC cells (Lane 3), using AASS polyclonal antibody (Cat # PAB17603).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — AASS
Entrez GeneID
10157Protein Accession#
Q9UDR5Gene Name
AASS
Gene Alias
LKR/SDH, LKRSDH, LORSDH
Gene Description
aminoadipate-semialdehyde synthase
Gene Ontology
HyperlinkGene Summary
This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq
Other Designations
alpha-aminoadipate semialdehyde synthase|aminoadipic semialdehyde synthase|lysine-2-oxoglutarate reductase|lysine-ketoglutarate reductase /saccharopine dehydrogenase
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Interactome
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Pathway
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