PSMD11 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PSMD11.
Immunogen
A synthetic peptide corresponding to internal of human PSMD11.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total PSMD11 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from 293 cells (Lane 1 and lane 3) and HepG2 cells (Lane 2), using PSMD11 polyclonal antibody (Cat # PAB17553).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — PSMD11
Entrez GeneID
5717Protein Accession#
O00231Gene Name
PSMD11
Gene Alias
MGC3844, Rpn6, S9, p44.5
Gene Description
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Omim ID
604449Gene Ontology
HyperlinkGene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. [provided by RefSeq
Other Designations
26S proteasome regulatory subunit 9|proteasome 26S non-ATPase subunit 11
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