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Last updated: 2017/3/26
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CYP2B6 polyclonal antibody

  • Catalog # : PAB17526
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CYP2B6.
  • Immunogen:
  • A synthetic peptide corresponding to internal of human CYP2B6.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody detects endogenous levels of total CYP2B6 protein.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    ELISA (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from HT-29 cells, using CYP2B6 polyclonal antibody (Cat # PAB17526).
    Peptide "+" means "with peptide blocking".
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1555
  • Gene Name:
  • CYP2B6
  • Gene Alias:
  • CPB6,CYP2B,CYPIIB6,IIB1,P450
  • Gene Description:
  • cytochrome P450, family 2, subfamily B, polypeptide 6
  • Gene Summary:
  • This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq
  • Other Designations:
  • cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6
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