COX6C polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from HUVEC cells, using COX6C polyclonal antibody (Cat # PAB17522).
Peptide "+" means "with peptide blocking".
Immunofluorescence
Immunofluorescence analysis of HepG2 cells, using COX6C polyclonal antibody (Cat # PAB17522).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of COX6C.
Immunogen
A synthetic peptide corresponding to internal of human COX6C.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of total COX6C protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:500-1:1000)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HUVEC cells, using COX6C polyclonal antibody (Cat # PAB17522).
Peptide "+" means "with peptide blocking".Immunofluorescence
Immunofluorescence analysis of HepG2 cells, using COX6C polyclonal antibody (Cat # PAB17522).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — COX6C
Entrez GeneID
1345Protein Accession#
P09669Gene Name
COX6C
Gene Alias
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Gene Description
cytochrome c oxidase subunit VIc
Omim ID
124090Gene Ontology
HyperlinkGene Summary
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse COX subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene COX6CP1 has been found on chromosomes 16p12. [provided by RefSeq
Other Designations
cytochrome c oxidase subunit VIc preprotein
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Interactome
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Pathway
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Disease
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