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Last updated: 2017/4/23
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COL6A3 polyclonal antibody

  • Catalog # : PAB17517
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of COL6A3.
  • Immunogen:
  • A synthetic peptide corresponding to internal of human COL6A3.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody detects endogenous levels of total COL6A3 protein.
  • Form:
  • Liquid
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:100)
    Immunofluorescence (1:500-1:1000)
    ELISA (1:40000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using COL6A3 polyclonal antibody (Cat # PAB17517).
    Peptide "+" means "with peptide blocking".
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of HeLa cells, using COL6A3 polyclonal antibody (Cat # PAB17517).
    Peptide "+" means "with peptide blocking".
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1293
  • Gene Name:
  • COL6A3
  • Gene Alias:
  • DKFZp686D23123,DKFZp686K04147,DKFZp686N0262,FLJ34702,FLJ98399
  • Gene Description:
  • collagen, type VI, alpha 3
  • Gene Summary:
  • This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described. [provided by RefSeq
  • Other Designations:
  • alpha 3 type VI collagen,collagen VI, alpha-3 polypeptide
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