COL4A6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of COL4A6.
Immunogen
A synthetic peptide corresponding to internal of human COL4A6.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total COL4A6 protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using COL4A6 polyclonal antibody (Cat # PAB17514).
Peptide "+" means "with peptide blocking".Immunofluorescence
Immunofluorescence analysis of HeLa cells, using COL4A6 polyclonal antibody (Cat # PAB17514).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — COL4A6
Entrez GeneID
1288Protein Accession#
Q14031Gene Name
COL4A6
Gene Alias
MGC88184
Gene Description
collagen, type IV, alpha 6
Gene Ontology
HyperlinkGene Summary
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023834|OTTHUMP00000023835|collagen IV, alpha-6 polypeptide|collagen alpha 6 type IV|collagen of basement membrane, alpha-6|dJ889N15.4 (Collagen Alpha 6(IV))|type IV alpha 6 collagen
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