CDK5RAP2 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human brain tissue using CDK5RAP2 polyclonal antibody (Cat # PAB17507).
Peptide "+" means "with peptide blocking".
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CDK5RAP2.
Immunogen
A synthetic peptide corresponding to internal of human CDK5RAP2.
Sequence
QMEHQKERNSFEER
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total CDK5RAP2 protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human brain tissue using CDK5RAP2 polyclonal antibody (Cat # PAB17507).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
-
Gene Info — CDK5RAP2
Entrez GeneID
55755Protein Accession#
Q96SN8Gene Name
CDK5RAP2
Gene Alias
C48, Cep215, DKFZp686B1070, DKFZp686D1070, KIAA1633, MCPH3
Gene Description
CDK5 regulatory subunit associated protein 2
Gene Ontology
HyperlinkGene Summary
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein may also be a substrate of neuronal CDC2-like kinase. Multiple transcript variants exist for this gene, but the full-length nature of only two has been determined. [provided by RefSeq
Other Designations
CDK5 activator-binding protein C48|OTTHUMP00000022800|OTTHUMP00000064031|centrosomal protein 215 kDa
-
Interactome
-
Disease
-
Publication Reference
-
Clinicopathological significance of S100 protein expression in cholangiocarcinoma.
Sato Y, Harada K, Sasaki M, Nakanuma Y.
Journal of Gastroenterology and Hepatology 2013 Aug; 28(8):1422.
-
Clinical and cellular features in patients with primary autosomal recessive microcephaly and a novel CDK5RAP2 mutation.
Issa L, Mueller K, Seufert K, Kraemer N, Rosenkotter H, Ninnemann O, Buob M, Kaindl AM, Morris-Rosendahl DJ.
Orphanet Journal of Rare Diseases 2013 Apr; 8:59.
Application：WB-Ce, Human, Human lymphocytes.
-
CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly.
Issa L, Kraemer N, Rickert CH, Sifringer M, Ninnemann O, Stoltenburg-Didinger G, Kaindl AM.
Cerebral Cortex (New York, N.Y. : 1991) 2013 Sep; 23(9):2245.
Application：IF, IP, WB, Human, HeLa cells.
-
Clinicopathological significance of S100 protein expression in cholangiocarcinoma.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com